While warfarin can be a lifesaver for patients suffering from atrial fibrillation and other conditions that may cause a fatal blood clot, the drug also has its drawbacks. Rare side effects include stroke, gangrene and death. The most common side effect - bleeding - can be life-threatening.

Tranexamic acid administration should be considered.

4-factor Prothrombin Complex Concentrate*, if available or 3-factor PCC and Fresh frozen plasma.How do you treat bleeding from warfarin overdose?Īny patient with a coagulopathy due to a vitamin K antagonist and life-threatening bleeding should receive the following treatment: Active, serious hemorrhage should be treated with four-factor prothrombin complex concentrate (PCC), if available. Significant superwarfarin poisoning may require many weeks of vitamin K 1 therapy. In the absence of serious or life-threatening hemorrhage, treatment with oral vitamin K 1 is recommended. Does vitamin K make your INR go up or down?.Can I eat oranges while taking warfarin?.Do blood thinners weaken your immune system?.What happens if your warfarin is too high?.How do you treat bleeding from warfarin overdose?.What is the treatment of warfarin toxicity?.

Antidote for warfarin overdose